(Z)-Broparestrol
(Z)-Broparestrol is a prostaglandin synthetase inhibitor with an IC50 of 7.0 μM in cattle. (Z)-Broparestrol inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes. (Z)-Broparestrol is applicable for acne-related research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 22393-63-1
- 分子式: C22H19Br
- 分子量:363.29
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
(Z)-Broparestrol (BROPARESTROL Z) inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes with an IC50 of 7.0 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 22393-63-1
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分子量 363.29
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分子式 C22H19Br
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SMILES
Br/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)\C3=CC=C(C=C3)CC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Gilbert J, et al. Inhibition of prostaglandin synthetase by di- and triphenylethylene derivatives: a structure-activity study. Journal of medicinal chemistry. 1983 May;26(5):693-9. [Content Brief]
[2]. Toscani S, et al. Overt and hidden polymorphism in the binary system involving the Z- and E- isomers of broparestrol. Int J Pharm. 2025 Jan 25;669:125060. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)