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Zubotamig

(別名: Gen1047)
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Based on 1 Customer Validation

Zubotamig (Gen1047) is an CD3E/VTCN1-targeting Ig(G1 -κ_G1 -λ2) type chimeric human antibody. The recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). Zubotamig induces T-cell mediated cytotoxicity of B7H4-positive tumor cells, triggers T-cell activation, and induces cytokine release from T cells in the presence of B7H4-expressing tumor cells. Zubotamig demonstrates antitumor activity in mouse patient-derived xenograft (PDX) models. Zubotamig can be used for the research of solid cancers (including breast, ovarian and lung cancer).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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  • 純度: 96.46%
  • CAS 番号: 2640279-10-1
  • 分子量:144.74 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Zubotamig
  • Experimental Validation Results for Zubotamig
  • Experimental Validation Results for Zubotamig
  • Zubotamig Chemical Structure
    Zubotamig 構造式
CAS 番号: 2640279-10-1
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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100 mg

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Assay Types
  • 1/16

    IgG1-lambda-kappa

  • 1/16

    Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Zubotamig. The EC50 for this effect is 17.19 ng/mL.

  • 1/16

    Immobilized B7-H4 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78073) can bind Zubotamig. The EC50 for this effect is 29.2 ng/mL.

  • Zubotamig Chemical Structure
    1/16
  • Zubotamig
  • Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Zubotamig. The EC50 for this effect is 17.19 ng/mL.
  • Immobilized B7-H4 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78073) can bind Zubotamig. The EC50 for this effect is 29.2 ng/mL.
  • IgG1-lambda-kappa