2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. JYL-79

JYL-79 is a TRPV1 agonist with the IC50 of 3.9 nM. JYL-79 can be used for study of neuropathic pain.

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JYL-79

JYL-79 Estructura química

No. CAS : 289902-64-3

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JYL-79 Related Antibodies

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TRPA1 TRPC3 TRPC4 TRPC5 TRPC6 TRPC7 TRPM8 TRPM2 TRPM3 TRPM4 TRPM7 TRPML1 TRPML2 TRPML3 TRPV1 TRPV2 TRPV3 TRPV4 TRPV6

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Descripciòn

JYL-79 is a TRPV1 agonist with the IC50 of 3.9 nM. JYL-79 can be used for study of neuropathic pain[1].

Cellular Effect
Cell Line Type Value Description References
CHO EC50
1.97 nM
Compound: 1
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells
In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cells
[PMID: 12825950]
CHO EC50
1.97 nM
Compound: 2
Agonist activity at rat TRPV1 expressed in CHO cells assessed as maximal calcium uptake
Agonist activity at rat TRPV1 expressed in CHO cells assessed as maximal calcium uptake
[PMID: 17035013]
Peso molecular

472.64

Fòrmula

C26H36N2O4S
No. CAS
SMILES

CC(C)(C)C(OCC(CNC(NCC1=CC=C(O)C(OC)=C1)=S)CC2=CC=C(C)C(C)=C2)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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JYL-79 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JYL-79289902-64-3JYL79JYL 79TRP ChannelTransient receptor potential channelssmooth musclerat isolated skeletal muscle arteriesInhibitorinhibitorinhibit

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Nombre del producto:
JYL-79
Cat. No.:
HY-117922
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