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Cat. No.: HY-165152

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KAS 08

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KAS 08 is an effective STING pathway activator in vitro and in vivo. KAS 08 enhances STING activity initiated by cGAMP.

For research use only. We do not sell to patients.

Purity: 99.9%
CAS No.: 203861-20-5
Formula: C₂₄H₂₀N₄O₆S
Molecular Weight:492.50

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

KAS 08 Chemical Structure

CAS No.: 203861-20-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

KAS 08 is an effective STING pathway activator in vitro and in vivo. KAS 08 enhances STING activity initiated by cGAMP.

Chemical Information

CAS No. 203861-20-5
Appearance Solid
Molecular Weight 492.50
Formula C₂₄H₂₀N₄O₆S
Color White to off-white
SMILES

O=C(C1=CC=C(C=C1)[N+]([O-])=O)N2C3=CC=C(S(=O)(N4C[C@H](C5=CC=CC=C5)NC4=O)=O)C=C3CC2
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jung HR, Jo S, Jeon MJ, et al. Development of Small-Molecule STING Activators for Cancer Immunotherapy. Biomedicines. 2021;10(1):33. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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