Antibacterial agent 319
Antibacterial agent 319 is an antibacterial and antitumor agent. Antibacterial agent 319 exhibits activity against E. coli and S. aureus. Antibacterial agent 319 also inhibits the growth of melanoma cells. Antibacterial agent 319 can be used in research on tumor bacterial infections such as melanoma.
For research use only. We do not sell to patients.
- Formula: C25H30FN5O3S
- Molecular Weight:499.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Antibacterial agent 319 (Compound 7b) potently inhibits the growth of B16-F10 mouse melanoma cells with an IC50 of 7.3 μM, and exhibits lower toxicity against normal HEK-293 cells (IC50 = 18.4 μM)[1].
Antibacterial agent 319 (62.5-500 μg/mL; 24 h) inhibits the growth of E. coli and S. aureus, with an MIC of 500 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Molecular Weight 499.60
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Formula C25H30FN5O3S
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SMILES
O=C(NNC(CCCCCCCCCCSC1=NN=C(C2=CC=C(F)C=C2)O1)=O)C3=CC=NC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 319 Related Classifications
HY-181120 Related Classifications
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