12-Ethoxynimbolinin E
12-Ethoxynimbolinin E is a nimbolinin-type limonoid found in the fruits of Melia toosendan. 12-Ethoxynimbolinin E induces cytotoxic activity against cancer cells. 12-Ethoxynimbolinin E can be used for the research of cancer, such as myeloid leukemia, and lung cancer.
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- CAS No.: 1941147-56-3
- 화학식: C35H44O8
- 분자량:592.72
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
12-Ethoxynimbolinin E (Compound 1) inhibits viability of HL-60, A-549, MCF-7, and SW480 human tumor cell lines with IC50 values of 21.5, 26.4, 25.2, and 31.8 μM, respectively, and does not inhibit viability of SMMC-7721 cells at concentrations up to 40 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1941147-56-3
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분자량 592.72
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화학식 C35H44O8
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SMILES
C[C@]12[C@@]3([H])[C@](OC[C@@]3([C@@H](C[C@@H]2OC(C4=CC=CC=C4)=O)O)C)([H])[C@H]([C@@]5([C@]1([H])C[C@@H](O[C@]6([H])C5=C([C@H](C7=COC=C7)C6)C)OCC)C)O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)