2-Cyanophenothiazine
Based on 1 Customer Validation
2-Cyanophenothiazine (Phenothiazine-2-carbonitrile) is a drug intermediate for synthesis of various active compounds.
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- Purity : 98.91%
- CAS No.: 38642-74-9
- 화학식: C13H8N2S
- 분자량:224.29
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-1080 | EC50 |
0.209 μM
Compound: P19
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Inhibition of erastin-induced ferroptosis in human HT-1080 cells assessed as cell viability incubated for 48 hrs by MTT assay
Inhibition of erastin-induced ferroptosis in human HT-1080 cells assessed as cell viability incubated for 48 hrs by MTT assay
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[PMID: 33065375] |
Chemical Information
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CAS No. 38642-74-9
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Appearance Solid
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분자량 224.29
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화학식 C13H8N2S
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Color Yellow to brown
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SMILES
N#CC1=CC2=C(C=C1)SC3=CC=CC=C3N2
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Synonyms
Phenothiazine-2-carbonitrile
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
DMSO : ≥ 100 mg/mL (445.85 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (242 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4585 mL | 22.2926 mL | 44.5851 mL | 111.4628 mL |
| 5 mM | 0.8917 mL | 4.4585 mL | 8.9170 mL | 22.2926 mL | |
| 10 mM | 0.4459 mL | 2.2293 mL | 4.4585 mL | 11.1463 mL | |
| 15 mM | 0.2972 mL | 1.4862 mL | 2.9723 mL | 7.4309 mL | |
| 20 mM | 0.2229 mL | 1.1146 mL | 2.2293 mL | 5.5731 mL | |
| 25 mM | 0.1783 mL | 0.8917 mL | 1.7834 mL | 4.4585 mL | |
| 30 mM | 0.1486 mL | 0.7431 mL | 1.4862 mL | 3.7154 mL | |
| 40 mM | 0.1115 mL | 0.5573 mL | 1.1146 mL | 2.7866 mL | |
| 50 mM | 0.0892 mL | 0.4459 mL | 0.8917 mL | 2.2293 mL | |
| 60 mM | 0.0743 mL | 0.3715 mL | 0.7431 mL | 1.8577 mL | |
| 80 mM | 0.0557 mL | 0.2787 mL | 0.5573 mL | 1.3933 mL | |
| 100 mM | 0.0446 mL | 0.2229 mL | 0.4459 mL | 1.1146 mL |
2-Cyanophenothiazine Related Classifications
HY-I0178 Related Classifications
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