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United States

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Cat. No.: HY-185983

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Ale-a12K2

Ale-a12K2 is a peptide-based ionizable lipid modified with bone-binding alendronate. Ale-a12K2 mediates targeted delivery of mRNA to bone tissues. Ale-a12K2 increases mRNA expression levels in the femur and tibia.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3113145-84-6
화학식: C₁₂₈H₂₅₈N₁₀O₁₃P₂
분자량:2207.42

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Ale-a12K2 Chemical Structure

CAS No.: 3113145-84-6

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 3113145-84-6
분자량 2207.42
화학식 C₁₂₈H₂₅₈N₁₀O₁₃P₂
SMILES

CCCCCCCCCCCCN(CCCC[C@H](NC(CCC(NCCCC(P(O)(O)=O)(O)P(O)(O)=O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)CCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)CCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)CCCCCCCCCCCC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Lin Y, et al. Tissue-specific mRNA delivery and prime editing with peptide-ionizable lipid nanoparticles. Nature materials. 2026 Jan;25(1):133-145. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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