Antimicrobial agent-26
Antimicrobial agent-26 is a potent antimicrobial agent and can mitigate antibiotic resistancein vitro.
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- CAS No.: 3026743-44-9
- 화학식: C27H40N4O4S
- 분자량:516.70
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | CC50 |
50.12 μM
Compound: 6d
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Cytotoxicity against HEK293T cells assessed as cell viability incubated for 6 hrs by CCK8 assay
Cytotoxicity against HEK293T cells assessed as cell viability incubated for 6 hrs by CCK8 assay
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[PMID: 37879170] |
| HepG2 | CC50 |
84.64 μM
Compound: 6d
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Cytotoxicity against human HepG2 cells assessed as cell viability incubated for 6 hrs by CCK8 assay
Cytotoxicity against human HepG2 cells assessed as cell viability incubated for 6 hrs by CCK8 assay
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[PMID: 37879170] |
Chemical Information
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CAS No. 3026743-44-9
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분자량 516.70
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화학식 C27H40N4O4S
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SMILES
CN(C)C1=NC=NC(SCC(O[C@H]2[C@@]([C@H](C)CC3)(C)[C@@](C(CC4)=O)([H])[C@]43[C@@H](C)[C@H](O)[C@@](C=C)(C)C2)=O)=N1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antimicrobial agent-26 Related Classifications
HY-155364 Related Classifications
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