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Cat. No.: HY-118661

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BDM14471

BDM14471 is a selective inhibitor of hydroxamate aminopeptidase M1 (PfAM1), with the IC₅₀ of 6 nM.

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CAS No.: 934618-96-9
화학식: C₁₇H₁₅FN₂O₃
분자량:314.31

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

BDM14471 Chemical Structure

CAS No.: 934618-96-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

BDM14471 is a selective inhibitor of hydroxamate aminopeptidase M1 (PfAM1), with the IC₅₀ of 6 nM^[1].

All Aminopeptidase Isoforms :

CD13
LTA4H

Cellular Effect

Cell Line	Type	Value	Description	References
MRC5	IC₅₀	32 μM Compound: 2, BDM14471	Cytotoxicity against human MRC5 SV2 cells after 72 hrs by resazurin fluorimetric analysis Cytotoxicity against human MRC5 SV2 cells after 72 hrs by resazurin fluorimetric analysis	[PMID: 23176597]

Chemical Information

CAS No. 934618-96-9
분자량 314.31
화학식 C₁₇H₁₅FN₂O₃
SMILES

O=C(/C(C(NO)=O)=C/C1=CC=CC=C1)NCC2=CC=C(C=C2)F
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rebecca Deprez-Poulain, et al. Structure–Activity Relationships and Blood Distribution of Antiplasmodial Aminopeptidase-1 Inhibitors. J Med Chem. 2012 Dec 27;55(24):10909-17. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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BDM14471

All Aminopeptidase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

BDM14471 Related Classifications

HY-118661 Related Classifications