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Cat. No.: HY-121277

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Benzoflavine

Benzoflavine is an acridine dye and photodynamic sensitizer that regulates embryonic development. Benzoflavine can adsorb to the surface of Arbacia sea urchin egg cell membranes, enhance the sensitivity of highly physiologically active embryonic regions to visible light radiation, and induce anterior-posterior developmental differences; at high concentrations, it can independently inhibit embryonic development without illumination, and its photosensitive response range covers the blue-violet region of visible light. Benzoflavine can be used in research fields such as developmental biology, organic synthesis, and photobiochemistry.

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CAS No.: 477-74-7
화학식: C₂₁H₁₉N₃
분자량:313.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Benzoflavine Chemical Structure

CAS No.: 477-74-7

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

In Vitro

Benzoflavine (in dilute seawater solution; gradient visible light irradiation) adsorbs to the cell membrane surface of fertilized Arbacia punctulata sea urchin eggs, inducing a photosensitizing effect of embryonic tissues to visible light radiation. Light treatment of this system induces four types of developmental phenotypes in Arbacia pluteus larvae, including irreversible differentiation inhibition, differentiation recovery after transient inhibition, complete overall tissue recovery, and tissue compensatory adaptation^[1].
Benzoflavine (dilute seawater solution; continuous exposure to diffuse sunlight) induces differential adaptation and hyperplasia of the anterior median embryonic tissue in Arbacia larvae^[1].
Benzoflavine (high-concentration seawater solution; incubated in the dark) inhibits the development of oral lobes and aboral arms in Arbacia embryos, resulting in a differential developmental inhibition effect^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 477-74-7
분자량 313.40
화학식 C₂₁H₁₉N₃
SMILES

CC1=C(C=C2N=C3C=C(C(C)=CC3=C(C2=C1)C4=CC=CC=C4)N)N
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Hinrichs M A. Modification of development on the basis of differential susceptibility to radiation. II. Arbacia and visible light following sensitization. Biological Bulletin, 1926, 50(1).

[2]. Friedrich M. Synthesis of nitro acridine derivatives. Louisville: University of Louisville, 1926.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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