BRD1554
BRD1554 is an inhibitor of the thioesterase domain of polyketide synthase 13 (Pks13) from Mycobacterium tuberculosis, and exhibits selective activity against Pks13-expressing strains. Pks13 is a polyketide synthase essential for the synthesis of branched-chain fatty acids in mycobacteria. BRD1554 serves as a scaffold molecule for anti-Mycobacterium tuberculosis agents. BRD1554 can be used in the research of tuberculosis.
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- 화학식: C19H19FN4O3
- 분자량:370.38
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
BRD1554 (1-100 μM; 14 days) selectively hypersensitizes Pks13 and Rv2581c hypomorphic Mtb strains, with a maximal confidence PCL match to Pks13 inhibitors, indicating it targets the Pks13 thioesterase domain[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 370.38
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화학식 C19H19FN4O3
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SMILES
CC1=NOC(CC2COCC2NC(C3=CC(C4=CC=C(C=C4)F)=NN3)=O)=C1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD1554 Related Classifications
HY-183968 Related Classifications
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