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Cat. No.: HY-184320

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CDK-IN-20

CDK-IN-20 is a selective CDK2 inhibitor with an IC₅₀ value of <10 nM. CDK-IN-20 can be used for cancer research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2776187-63-2
화학식: C₁₆H₁₇F₃N₄O₅S
분자량:434.39

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CDK-IN-20 Chemical Structure

CAS No.: 2776187-63-2

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

CDK-IN-20 is a selective CDK2 inhibitor with an IC₅₀ value of <10 nM. CDK-IN-20 can be used for cancer research^[1].

All CDK Isoforms :

In Vitro

CDK-IN-20 (Compound E7) exhibits moderate inhibitory activity against CDK1, CDK4, and CDK6, with IC₅₀ values ranging from 100 nM to 1 μM; it shows extremely weak inhibitory activity against CDK7 and CDK9, with IC₅₀ > 1 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2776187-63-2
분자량 434.39
화학식 C₁₆H₁₇F₃N₄O₅S
SMILES

FC(F)(F)C(C(O[C@H]1[C@H](COCC1)O)=N2)=CN=C2NC3=CC=C(C=C3)S(N)(=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Dai Cheng, et al. Aminoheteroaryl kinase inhibitors. WO2023093769A1.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References

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수량:
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CDK-IN-20

All CDK Isoforms