EEKLIVVAF
EEKLIVVAF is a pepitide, can be recognized on HLA-B44 by the anti-melanoma cytolytic T-cell (CTL) clone LB33- CTL-159/5.
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- CAS No.: 188818-21-5
- 화학식: C50H82N10O14
- 분자량:1047.24
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
In Vitro
EEKLIVVAF can be recognized by CTL clone on C1RB*4402 and C1R-B*4403 cells, and (45 ng/mL and 160 ng/mL, respectively; 30 min; 20 °C) shows the ability to compete with a standard peptide for binding to HLA-B*4402 and HLA-B*4403 molecules[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 188818-21-5
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분자량 1047.24
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화학식 C50H82N10O14
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Sequence Shortening
EEKLIVVAF
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Herman J, et al. Differences in the recognition by CTL of peptides presented by the HLA-B*4402 and the HLA-B*4403 molecules which differ by a single amino acid. Tissue Antigens. 1999 Feb;53(2):111-21. [Content Brief]
[2]. Herman J, et al. A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3. Immunogenetics. 1996;43(6):377-83. [Content Brief]
[3]. Coulie PG, et al. A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7976-80. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)