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Cat. No.: HY-120248

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FR221647

FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. FR221647 is not cytotoxic at a concentration of 100 μM.

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CAS No.: 256461-28-6
화학식: C₁₄H₁₇N₃O₂
분자량:259.30

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

FR221647 Chemical Structure

CAS No.: 256461-28-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

FR221647 is an orally active non-nucleoside inhibitor of adenosine deaminase. FR221647 is not cytotoxic at a concentration of 100 μM^[1].

In Vitro

FR221647 is an inhibitor of human adenosine deaminase (ADA) with a K_i value of 5.9 μM^[1]. FR221647 is not cytotoxic at a concentration of 100 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 256461-28-6
분자량 259.30
화학식 C₁₄H₁₇N₃O₂
SMILES

O=C(C1=CN(C(CO)CCC2=CC=CC=C2)C=N1)N
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Terasaka T, et al. Structure-based de novo design of non-nucleoside adenosine deaminase inhibitors. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1115-8. [Content Brief]

Calculators

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Concentration _(start) Concentration _(start)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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