EPHA10 - EPH receptor A10 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 284656

About EPHA10

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:37,713,880-37,765,120 (from NCBI)

This gene has 11 transcripts (splice variants), 110 orthologues and 53 paralogues. Biased expression in testis (RPKM 7.0), colon (RPKM 2.9) and 7 other tissues.

Summary

Ephrin receptors, the largest subfamily of Receptor Tyrosine Kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells (Aasheim et al., 2005 [PubMed 15777695]). See MIM 179610 for additional background on Eph Receptors and Ephrins.[supplied by OMIM, Mar 2008]

EPHA10 Products (2)

mRNA Protein Name
NM_001099439.2 NP_001092909.1 ephrin type-A receptor 10 isoform 3 precursor
NM_173641.3 NP_775912.2 ephrin type-A receptor 10 isoform 2 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15777695 GOA
enables transmembrane-ephrin receptor activity IDA
IDA: Inferred from direct assay
15777695 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EPHA10 Protein Structure

Ephrin_lbd

Ephrin_lbd: Ephrin receptor ligand binding domain (35 - 211)

fn3

fn3: Fibronectin type III domain (339 - 432)

fn3

fn3: Fibronectin type III domain (464 - 533)

EphA2_TM

EphA2_TM: Ephrin type-A receptor 2 transmembrane domain (567 - 642)

Pkinase_Tyr

Pkinase_Tyr: Protein tyrosine kinase (646 - 900)

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (934 - 994)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1008 a.a.
Protein Preferred Names Protein Names

ephrin type-A receptor 10

  • EphA10s protein

Recombinant EPHA10 Proteins

Cat. No. 상품명 Accession Purity
HY-P77929 EPHA10 Protein, Human (HEK293, His) Q5JZY3-1 (E34-A565) ≥ 95%, as determined by Bis-Tris PAGE.

EPHA10 Antibodies

Cat. No. 상품명 신청 Reactivity
HY-P85137 EphA10 Antibody (YA4829) WB, ELISA Human

Related Diseases

Diseases Alias
Hypogonadotropic Hypogonadism 6 With Or Without Anosmia

  • HH6

  • Kallmann Syndrome 6

  • Kal6

  • Hypogonadotropic Hypogonadism, Type 6 With/Without Anosmia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS04425 EPHA10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19256 Epha10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25745 Epha10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus EPHA10 MGD MGI:3586824
Felis catus EPHA10 VGNC VGNC:107531
Macaca mulatta EPHA10 VGNC VGNC:99905
Rattus norvegicus EPHA10 RGD RGD:1562679
Bos taurus EPHA10 VGNC VGNC:28533
Others EPHA10 NCBI