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Lefelsiran

(Synonyms: NN-6020)

Lefelsiran (NN-6020) is a siRNA targeted to ALDH2. It is used for the study of alcohol use disorder.

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  • Lefelsiran Chemical Structure
    Lefelsiran Chemical Structure
CAS No.: 2765645-87-0
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주변의 대리점 찾기 Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All Aldehyde Dehydrogenase (ALDH) Isoforms

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100 mg

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  • Lefelsiran Chemical Structure
    Lefelsiran Chemical Structure RNA, ([4'-de(hydroxymethyl)-4'-[(hydroxymethoxyphosphinyl)methoxy]]Um-sp-(2'-deoxy-2'-fluoro)A-sp-(2'-deoxy-2'-fluoro)A-sp-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Am-Gm-Um-Um-Um-Cm-(2'-deoxy-2'-fluoro)A-Um-Cm-Cm-Am-Cm-Cm-sp-Gm-sp-Gm), complex with RNA (Gm-sp-Gm-Um-Gm-Gm-Am-Um-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Cm-Um-Cm-Am-Gm-Um-Um-Um-Am-Gm-Cm-Am-Gm-Cm-Cm-Gm-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-Gm-Gm-Cm-Um-Gm-Cm) (1:1)
    1/16
  • RNA, ([4'-de(hydroxymethyl)-4'-[(hydroxymethoxyphosphinyl)methoxy]]Um-sp-(2'-deoxy-2'-fluoro)A-sp-(2'-deoxy-2'-fluoro)A-sp-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)C-Um-(2'-deoxy-2'-fluoro)G-Am-Gm-Um-Um-Um-Cm-(2'-deoxy-2'-fluoro)A-Um-Cm-Cm-Am-Cm-Cm-sp-Gm-sp-Gm), complex with RNA (Gm-sp-Gm-Um-Gm-Gm-Am-Um-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-(2'-deoxy-2'-fluoro)A-Cm-Um-Cm-Am-Gm-Um-Um-Um-Am-Gm-Cm-Am-Gm-Cm-Cm-Gm-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-[2'-O-[[2-[2-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]ethoxy]ethoxy]methyl]]A-Gm-Gm-Cm-Um-Gm-Cm) (1:1)