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Cat. No.: HY-167898

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MeS-IMPY

MeS-IMPY is a ligand of β-amyloid plaques. MeS-IMPY shows a high binding affinity to β-amyloid plaques extracted from Alzheimer's disease (AD) human brains or AD brain homogenates compared to IMPY (K_i=7.93 and 8.95 nM, respectively). [¹¹C]MeS-IMPY is a potential radioligand for imaging β-amyloid plaques with positron emission tomography (PET).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 955376-42-8
화학식: C₁₆H₁₇N₃S
분자량:283.39

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

MeS-IMPY Chemical Structure

CAS No.: 955376-42-8

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 955376-42-8
분자량 283.39
화학식 C₁₆H₁₇N₃S
SMILES

CSC1=CN2C=C(C3=CC=C(N(C)C)C=C3)N=C2C=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Seneca N, et al. Brain and whole-body imaging in nonhuman primates with [11C]MeS-IMPY, a candidate radioligand for beta-amyloid plaques. Nucl Med Biol. 2007 Aug;34(6):681-9. [Content Brief]

[2]. Seneca N, et al. Low retention of [S-methyl-11C] MeS-IMPY to β-amyloid plaques in patients with Alzheimer's disease[J]. Current Radiopharmaceuticals, 2009, 2(2): 129-136.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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