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Cat. No.: HY-119014

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NU-8231

NU-8231 (Compound 2) is a p53-MDM2 binding inhibitor with an IC₅₀ of 5.3-200 μM for inhibiting the p53-MDM2 interaction. NU-8231 is applicable for cancer research.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 878022-36-7
화학식: C₂₆H₂₆ClNO₅
분자량:467.95

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

NU-8231 Chemical Structure

CAS No.: 878022-36-7

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

NU-8231 (Compound 2) is a p53-MDM2 binding inhibitor with an IC₅₀ of 5.3-200 μM for inhibiting the p53-MDM2 interaction. NU-8231 is applicable for cancer research^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
SJSA-1	IC₅₀	5.3 μM Compound: 2q	Inhibitory concentration against MDM2-p53 interaction in SJSA human sarcoma cells Inhibitory concentration against MDM2-p53 interaction in SJSA human sarcoma cells	[PMID: 15713419]

Chemical Information

CAS No. 878022-36-7
분자량 467.95
화학식 C₂₆H₂₆ClNO₅
SMILES

O=C1C=2C=CC=CC2C(OCC3=CC(OC)=C(O)C(OC)=C3)(C4=CC=C(Cl)C=C4)N1CCC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Beretta GL, et al. Small molecules targeting p53 to improve antitumor therapy. Mini Rev Med Chem. 2008;8(9):856-868. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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