P-gp modulator-7

P-gp modulator-7 (Compound 9e) is a P-glycoprotein (P-gp) inhibitor. P-gp modulator-7 occupies the channel entrance of P-gp with a unique T-shaped configuration, hindering the peristaltic extrusion mechanism of transmembrane domains TM12 and TM9, thereby inhibiting P-gp from pumping drugs out of cells and reversing the multidrug resistance (MDR) of tumor cells. P-gp modulator-7 is promising for research of cancers.

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  • 화학식: C36H60N2O5
  • 분자량:600.87
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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