P-gp modulator-7
P-gp modulator-7 (Compound 9e) is a P-glycoprotein (P-gp) inhibitor. P-gp modulator-7 occupies the channel entrance of P-gp with a unique T-shaped configuration, hindering the peristaltic extrusion mechanism of transmembrane domains TM12 and TM9, thereby inhibiting P-gp from pumping drugs out of cells and reversing the multidrug resistance (MDR) of tumor cells. P-gp modulator-7 is promising for research of cancers.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C36H60N2O5
- 분자량:600.87
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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분자량 600.87
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화학식 C36H60N2O5
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SMILES
O=C(O[C@@H]1C[C@@]2([C@]3(CCC(C(C)([C@]3([H])CC[C@]2([C@@]4(CC[C@]([C@]5(C)CC[C@H](O5)C(C)(O)C)([C@@]14[H])[H])C)C)C)=O)C)[H])CN6CCNCC6
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)