PDE3/4-IN-3
PDE3/4-IN-3 (Compound 7) is an orally active dual PDE3/4 inhibitor with IC50 s of 0.17 and ≤50 nM for PDE3A and PDE4B2, respectively. PDE3/4-IN-3 significantly inhibits methacholine-induced bronchoconstriction in guinea pigs. PDE3/4-IN-3 can be used for chronic obstructive pulmonary disease (COPD) and asthma research.
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- CAS No.: 2939748-69-1
- 화학식: C26H28D3N5O4
- 분자량:480.57
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
[1]|
PDE3A 0.17 nM (IC50) |
PDE4B2 ≤50 nM (IC50) |
신청
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2939748-69-1
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Unlabeled CAS 1884461-72-6
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분자량 480.57
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화학식 C26H28D3N5O4
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SMILES
O=C(N1C(C2=CC(OC([2H])([2H])[2H])=C(OC)C=C2CC1)=C/3)N(CCNC(N)=O)C3=N\C4=C(C=C(C)C=C4C)C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PDE3/4-IN-3 Related Classifications
HY-176524S Related Classifications
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