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Cat. No.: HY-156090

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PK-10

PK-10 is a synergistic antibacterial agent of Fluconazole (HY-B0101) and has strong antifungal activity against a variety of Fluconazole-resistant Candida albicans strains. PK-10 combined with Fluconazole can inhibit hyphae formation and induce the accumulation of reactive oxygen species. It further causes damage to mitochondrial membrane potential, reduces intracellular ATP content, and leads to mitochondrial dysfunction.

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CAS No.: 3074451-41-2
화학식: C₃₅H₃₆F₃N₅O
분자량:599.69

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

PK-10 Chemical Structure

CAS No.: 3074451-41-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 3074451-41-2
분자량 599.69
화학식 C₃₅H₃₆F₃N₅O
SMILES

O=C(C1=CC=C(N2CCN(CC2)CC3=CC=C(C(F)(F)F)C=C3)C=C1)/C=C/C4=CC5=C(N=C4N6CCN(CC6)C)C=CC=C5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sun A, et al. Optimization and antifungal activity of quinoline derivatives linked to chalcone moiety combined with FLC against Candida albicans. Eur J Med Chem. 2023 Nov 15;260:115782.. . [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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