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Cat. No.: HY-174153

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PSB-22219

PSB-22219 is a highly selective non-nucleotidic ligand acting on P2Y₁₂ receptors (K_D=4.57 nM). PSB-22219 is promising for research of P2Y₁₂ receptor-associated neuroinflammation.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1404529-43-6
화학식: C₂₆H₂₆N₄O₄
분자량:458.51

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

PSB-22219 Chemical Structure

CAS No.: 1404529-43-6

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

PSB-22219 is a highly selective non-nucleotidic ligand acting on P2Y₁₂ receptors (K_D=4.57 nM). PSB-22219 is promising for research of P2Y₁₂ receptor-associated neuroinflammation^[1].

All P2Y Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	0.9 nM Compound: 50a	Displacement of [33P]2MeS-ADP from P2Y12 receptor (unknown origin) transfected in CHO cells after 30 mins by scintillation counting analysis Displacement of [33P]2MeS-ADP from P2Y12 receptor (unknown origin) transfected in CHO cells after 30 mins by scintillation counting analysis	[PMID: 25075638]

Chemical Information

CAS No. 1404529-43-6
분자량 458.51
화학식 C₂₆H₂₆N₄O₄
SMILES

CC1=CC=C2C(C(C(NC3=CC=C(N4N=CC(C(CCC)=O)=C4C)C=C3)=O)=CN2CC(O)=O)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Al-Hroub H, et al. Selective, Non-nucleotidic Radiotracer for P2Y12 Receptors: Design, Synthesis, Characterization, and Imaging of Brain Slices. J Med Chem. 2025 Jun 12;68(11):11279-11298. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
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수량:
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PSB-22219

All P2Y Receptor Isoforms