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Cat. No.: HY-190191

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QC-65

QC-65 is a HO-1/HO-2 inhibitor with IC₅₀ = 4.0 μM for HO-1 and IC₅₀ = 11.3 μM for HO-2. QC-65 can be used in research on HO-1-mediated related diseases, such as cancer.

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CAS No.: 741628-94-4
화학식: C₁₃H₁₄N₂O
분자량:214.26

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

QC-65 Chemical Structure

CAS No.: 741628-94-4

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

QC-65 is a HO-1/HO-2 inhibitor with IC₅₀ = 4.0 μM for HO-1 and IC₅₀ = 11.3 μM for HO-2. QC-65 can be used in research on HO-1-mediated related diseases, such as cancer^[1].

IC₅₀ & Target

^[1]

HO-1

4.0 μM (IC₅₀)

HO-2

11.3 μM (IC₅₀)

All Heme Oxygenase (HO) Isoforms :

HO-1
HO-2

In Vitro

QC-65 (1-100 μM; 60 min at 37 °C) inhibits rat spleen HO-1 and rat brain HO-2 with IC₅₀ values of 4.0 μM and 11.3 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 741628-94-4
분자량 214.26
화학식 C₁₃H₁₄N₂O
SMILES

O=C(CCC1=CC=CC=C1)CN2C=CN=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Fallica AN, et al. Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent Antiproliferative Activity. Journal of medicinal chemistry. 2021 Sep 23;64(18):13373-13393. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

견적 받기

Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

QC-65

All Heme Oxygenase (HO) Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

QC-65 Related Classifications

HY-190191 Related Classifications

Bioz

Keywords

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