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Cat. No.: HY-123452

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SCH 30497

SCH 30497 is a potent and orally active analgesic agent. SCH 30497 exhibits analgesic activity in the rat yeast-induced paw pain model, the mouse acetic acid-induced writhing test, and the squirrel monkey electric shock titration test. SCH 30497 can be used in pain research.

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CAS No.: 83674-78-6
화학식: C₂₁H₂₄N₄O
분자량:348.44

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

SCH 30497 Chemical Structure

CAS No.: 83674-78-6

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

In Vivo

SCH 30497 demonstrats dose-dependent analgesic effects in a rat model of yeast-induced paw pain; at peak efficacy, the ED₅₀ values (in mg/kg) for oral, subcutaneous, intramuscular, and intravenous administration were 4.7, 5.7, 6.4, and 1.4, respectively^[1].
SCH 30497 also exhibits analgesic activity in the mouse acetic acid-induced writhing test (ED₅₀ = 1.9 mg/kg, oral administration) and the squirrel monkey shock titration test (ED₅₀ = 14.5 mg/kg, oral administration)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 83674-78-6
분자량 348.44
화학식 C₂₁H₂₄N₄O
SMILES

O=C1N(N=C2C=CC=CN21)CCCN3CC=C(CC3)C4=CC=CC=C4C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Chipkin RE, et al. Pharmacological effects of SCH 30497--a novel analgesic substance. Arch Int Pharmacodyn Ther. 1985 Nov;278(1):23-44. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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