H-HomoArg-OH-13C7,15N4 hydrochloride
Based on 1 Customer Validation
H-HomoArg-OH-13C7,15N4 hydrochloride (L-Homoarginine-13C7,15N4 hydrochloride) is the 15N, 13C-labeled H-HomoArg-OH (hydrochloride) (HY-W012340). H-HomoArg-OH hydrochloride (L-Homoarginine hydrochloride) is an orally active endogenous non-protein amino acid. H-HomoArg-OH hydrochloride acts as a weak alternative substrate for NOS and interferes with NO production, selectively inhibits tissue-nonspecific alkaline phosphatase (TNAP), and suppresses the uptake of arginine by y+-type transporters (system y+). H-HomoArg-OH hydrochloride increases tissue hArg concentrations in vivo, regulates amino acid homeostasis, and improves renal function and pathological features of diabetic nephropathy. H-HomoArg-OH hydrochloride can be used in studies related to diabetes and cardiomyopathy.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 2483830-23-3
- Formula: 13C7H17Cl15N4O2
- Molecular Weight:235.61
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Endogenous Metabolite Isoforms
More
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 2483830-23-3
-
Unlabeled CAS 1483-01-8
-
Appearance Solid
-
Molecular Weight 235.61
-
Formula 13C7H17Cl15N4O2
-
Color White to off-white
-
SMILES
O[13C]([13C@@H]([15NH2])[13CH2][13CH2][13CH2][13CH2][15NH][13C]([15NH2])=[15NH])=O.Cl
-
Synonyms
L-Homoarginine-13C7,15N4 hydrochloride
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
-
Data Sheet (277 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- H-HomoArg-OH-13C7,15N4
- 2483830-23-3
- L-Homoarginine-13C7,15N4
- Isotope-Labeled Compounds
- Endogenous Metabolite
- Monocarboxylate Transporter
- Phosphatase
- AGAT
- diabetic nephropathy
- CCK receptor
- pancreatic beta cells
- serum alkaline phosphatase
- Sprague-Dawley rats
- lysine transporter
- takotsubo cardiomyopathy
- Ins2Akita mice
- nitric oxide synthase
- Inhibitor
- inhibitor
- inhibit