1. Metabolic Enzyme/Protease
    Immunology/Inflammation
  2. Endogenous Metabolite
    Aryl Hydrocarbon Receptor
  3. L-Kynurenine sulfate

L-Kynurenine sulfate 

Cat. No.: HY-104026B
Handling Instructions

L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype.

For research use only. We do not sell to patients.

L-Kynurenine sulfate Chemical Structure

L-Kynurenine sulfate Chemical Structure

CAS No. : 16055-80-4

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Top Publications Citing Use of Products

2 Publications Citing Use of MCE L-Kynurenine sulfate

    L-Kynurenine sulfate purchased from MCE. Usage Cited in: PLoS Pathog. 2020 Jul 17;16(7):e1008664.

    MT-1 cells are treated with Kynurenine (10, 50 μM) for 48 h or 4 days , then subjected to analyze the level of cytosolic AHR and nuclear AHR by immunoblot. After 4-days treatment, Kynurenine (10, 50 μM) remarkably induces the expression of CYP1A1 and plus-strand genes in a dose-dependent manner. Both groups efficiently triggered the production of Tax protein, p19 and p24, although the accumulation of gp46 is no apparent.
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    Description

    L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype[1].

    IC50 & Target

    Human Endogenous Metabolite

     

    Molecular Weight

    306.29

    Formula

    C10H14N2O7S

    CAS No.
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

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    Product Name:
    L-Kynurenine sulfate
    Cat. No.:
    HY-104026B
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