Cationic Lipids & Ionizable Lipids
Ale-a12K2
Cat. No.: HY-185983
CAS No.: 3113145-84-6
- Formula: C128H258N10O13P2
- Molecular Weight: 2207.42
a12k4E-Ca
Cat. No.: HY-185984
- Formula: C127H251N9O9
- Molecular Weight: 2048.41
a12k4E-Ca is a C-terminal glutamate-modified peptidogenic ionizable lipid that can be used for the preparation of lipid nanoparticles (LNPs). a12k4E-Ca preferentially accumulates in the spleen in vivo, acts as a carrier to mediate spleen-selective mRNA delivery, and enables spleen-specific Cre recombinase-mediated gene editing. a12k4E-Ca restores serum biochemical parameters and cytokines/chemokines. a12k4E-Ca can be used in studies related to LNP preparation.
