Phosphatidylinositols (PI)

Phosphatidylinositols, soya, sodium salts is a mixture of phosphatidylinositols. Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids between the different compartments of eukaryotic cells. They act by recruiting and/or activating effector proteins and thus are involved in regulating various cellular functions, such as vesicular budding, membrane fusion and cytoskeleton dynamics.

L-α-lysophosphatidylinositol Soy sodium is an endogenous ligand of GPR55. L-α-lysophosphatidylinositol Soy sodium is an endogenous lysophospholipid and endocannabinoid neurotransmitter that belongs to the class of lysophospholipids.

PtdIns-(345)-P3 (12-dipalmitoyl) sodium (Phosphatidylinositol tris-3,4,5-phosphate, 1,2-dipalmitoyl sodium) is a phosphatidylinositol 3,4,5-trisphosphate (PIP3) analog. PtdIns-(345)-P3 (12-dipalmitoyl) sodium can be incorporated in liposomes establish a backdrop of membrane phospholipids that closely mirrors in vivo conditions.

L-α-Phosphatidylinositol (liver, bovine) (sodium) is a biochemical reagent.

PtdIns-(3,4,5)-P3-biotin sodium is a Biotin-labeled PtdIns-(3,4,5)-P3 (PI(3,4,5)P3). PI(3,4,5)P3 is a substrate of nuclear phosphatidylinositol 5-phosphatase (PIP5Pase). PI(3,4,5)P3 binds to the N-terminus of RAP1 (repressor activator protein 1) and controls its DNA binding activity.

L-α-Phosphatidylinositol-4,5-bisphosphate ammonium is a key signaling lipid. L-α-Phosphatidylinositol-4,5-bisphosphate ammonium is an activator of PKC in the presence of calcium ions and phospholipid serine. L-α-Phosphatidylinositol-4,5-bisphosphate ammonium is also an antagonist of the KIR3.4 (ATP-sensitive potassium, KATP) channel. L-α-Phosphatidylinositol-4,5-bisphosphate ammonium can be used in research related to signal transduction, ion channel regulation, and membrane transport.

17:0-18:1 PI-d₅ (ammonium) is deuterium labeled 17:0-18:1 PI (ammonium).

(Rac)-16:0PI(3,5)P2-d₅ (ammonium) is deuterium labeled (Rac)-16:0PI(3,5)P2 (ammonium).

(Rac)-16:0 PI(5)P-d₅ (ammonium) is deuterium labeled (Rac)-16:0 PI(5)P (ammonium).

PtdIns-(1,2-dipalmitoyl) ammonium (DPPI) is a derivative of phosphatidylinositol (PtdIns) that contains C16:0 fatty acyl chains.

(Rac)-16:0 PI(5)P-d₅ diammonium is deuterium labeled (Rac)-16:0 PI(5)P diammonium.

PI(3,5)P2 diC16 is a synthetic inositol phospholipid. PI(3,5)P2 diC16 is a lipid molecule.

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol is an endogenous metabolite that is a cell membrane component.

Phosphatidylinositol-1,2-dioctanoyl sodium significantly inhibits transmembrane P-gp transport in a reproducible, cell line-independent, and substrate-independent manner. Phosphatidylinositol-1,2-dioctanoyl sodium plays an important role in signal transduction and cell movement.

Phosphatidylinositol tris-3,4,5-phosphate, 1,2-dioctanoyl (sodium) is an ester product.

18:0 PI is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.

Phosphatidylinositol bis-4,5-phosphate, 1,2-dioctanoyl sodiumis a phosphatidylinositol derivative that binds to ABCB5.

PtdIns-(4,5)-P2 (1,2-dioctanoyl) is a phosphatidylinositol derivative that binds to ABCB5.

16:0 PI(5)P-d₅ ammonium is the deuterium labeled 16:0 PI(5)P ammonium.

18:0 PI-d₆ (DSPI(18:0/18:0)-d₆) is the deuterated form of 18:0 PI. 18:0 PI is a membrane-bound signaling molecule that is associated with almost all aspects of cell physiology, including cell growth, metabolism, proliferation, and survival.