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Liriodenine (Synonyms: Spermatheridine; VLT045)

Cat. No.: HY-N3376
Handling Instructions

Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant Mitrephora sirikitiae and has anti-cancer activities. Liriodenine induces cell apoptosis, activates the intrinsic pathway by induction of caspase-3 and caspase-9.

For research use only. We do not sell to patients.

Liriodenine Chemical Structure

Liriodenine Chemical Structure

CAS No. : 475-75-2

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Description

Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant Mitrephora sirikitiae and has anti-cancer activities[1]. Liriodenine induces cell apoptosis, activates the intrinsic pathway by induction of caspase-3 and caspase-9[2].

In Vitro

Liriodenine is against P-388, KB, HT-29, MCF-7, A549, ASK and Hek-293 cells with IC50 values of 9.60 μM, 11.02 μM, 10.62 μM, 9.20 μM and 8.07μM, respectively.

Molecular Weight

275.26

Formula

C₁₇H₉NO₃

CAS No.

475-75-2

SMILES

O=C1C2=CC=CC=C2C3=C4OCOC4=CC5=CC=NC1=C53

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

LiriodenineSpermatheridineVLT045VLT 045VLT-045OthersP-388KBHT-29MCF-7A549ASKHek-293cancer ovarianInhibitorinhibitorinhibit

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