LMP7/LMP2-IN-1
LMP7/LMP2-IN-1 (Compound 19) is the orally active inhibitor for immunoproteasome subunits LMP7 and LMP2 with IC50 of 257 and 10 nM. LMP7/LMP2-IN-1 reduces the generation of antibody, downregulates the cells in spleen germinal center B and in plasma in NP-OVA-immunized mice, and can be used in research about autoimmune diseases.
For research use only. We do not sell to patients.
- CAS No.: 3053755-09-9
- Formula: C16H27BN4O3
- Molecular Weight:334.22
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 257 nM (LMP7); 10 nM (LMP2); 44.6 μM (β5c)
Chemical Information
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CAS No. 3053755-09-9
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Molecular Weight 334.22
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Formula C16H27BN4O3
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SMILES
OB(O)[C@@H](NC(C1=CN(C2CCCCC2)N=N1)=O)C3CCCCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LMP7/LMP2-IN-1 Related Classifications
HY-162754 Related Classifications
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