Loteprednol Etabonate-d5
Based on 1 Customer Validation
Loteprednol Etabonate-d5 is a deuterium labeled Loteprednol etabonate. Loteprednol etabonate (LE) is an orally active "soft" steroid belonging to a unique class of glucocorticoids. Loteprednol etabonate (LE) exhibits anti-inflammatory activity and has been used in optometry and ophthalmology.
For research use only. We do not sell to patients.
- Purity: 95.73%
- CAS No.: 2026643-11-6
- Formula: C24H26D5ClO7
- Molecular Weight:471.98
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2026643-11-6
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Unlabeled Cas 82034-46-6
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Appearance Solid
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Molecular Weight 471.98
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Formula C24H26D5ClO7
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Color White to off-white
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SMILES
C[C@@]12[C@](C(OCCl)=O)(OC(OC([2H])([2H])C([2H])([2H])[2H])=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (211.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Howes JF. Loteprednol etabonate: a review of ophthalmic clinical studies. Pharmazie. 2000 Mar;55(3):178-83. [Content Brief]
[2]. Pavesio CE, Decory HH. Treatment of ocular inflammatory conditions with loteprednol etabonate. Br J Ophthalmol. 2008 Apr;92(4):455-9. [Content Brief]
[3]. Comstock TL, Decory HH. Advances in corticosteroid therapy for ocular inflammation: loteprednol etabonate. Int J Inflam. 2012;2012:789623. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.1187 mL | 10.5937 mL | 21.1873 mL | 52.9683 mL |
| 5 mM | 0.4237 mL | 2.1187 mL | 4.2375 mL | 10.5937 mL | |
| 10 mM | 0.2119 mL | 1.0594 mL | 2.1187 mL | 5.2968 mL | |
| 15 mM | 0.1412 mL | 0.7062 mL | 1.4125 mL | 3.5312 mL | |
| 20 mM | 0.1059 mL | 0.5297 mL | 1.0594 mL | 2.6484 mL | |
| 25 mM | 0.0847 mL | 0.4237 mL | 0.8475 mL | 2.1187 mL | |
| 30 mM | 0.0706 mL | 0.3531 mL | 0.7062 mL | 1.7656 mL | |
| 40 mM | 0.0530 mL | 0.2648 mL | 0.5297 mL | 1.3242 mL | |
| 50 mM | 0.0424 mL | 0.2119 mL | 0.4237 mL | 1.0594 mL | |
| 60 mM | 0.0353 mL | 0.1766 mL | 0.3531 mL | 0.8828 mL | |
| 80 mM | 0.0265 mL | 0.1324 mL | 0.2648 mL | 0.6621 mL | |
| 100 mM | 0.0212 mL | 0.1059 mL | 0.2119 mL | 0.5297 mL |
Loteprednol Etabonate-d5 Related Classifications
HY-17358S Related Classifications
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