2. Anti-infection
  3. Bacterial
  4. LY 255262

LY 255262 is an antibacterial agent. LY 255262 exhibits potent inhibitory effects against a variety of Gram-positive and Gram-negative bacteria in vitro. LY 255262 has MIC values of 64, 0.25, 0.5, 0.25, 0.25, 1, and 1 μg/mL for Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenza, Escherichia coli, Klebsiella, Enterobacter aerogenes, and Serratia, respectively. LY 255262 has a relatively weak inhibitory effect on Pseudomonas (MIC >128 μg/mL). LY 255262 can be used in antibacterial research.

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LY 255262

LY 255262 Chemical Structure

CAS No. : 122620-16-0

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LY 255262 Related Antibodies

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Description

LY 255262 is an antibacterial agent. LY 255262 exhibits potent inhibitory effects against a variety of Gram-positive and Gram-negative bacteria in vitro. LY 255262 has MIC values of 64, 0.25, 0.5, 0.25, 0.25, 1, and 1 μg/mL for Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenza, Escherichia coli, Klebsiella, Enterobacter aerogenes, and Serratia, respectively. LY 255262 has a relatively weak inhibitory effect on Pseudomonas (MIC >128 μg/mL). LY 255262 can be used in antibacterial research[1].

Cellular Effect
Cell Line Type Value Description References
MRC5 CC50
60 μM
Compound: 31
Concentration required to reduce MRC-5 cell growth by 50%
Concentration required to reduce MRC-5 cell growth by 50%
[PMID: 10966740]
MRC5 IC50
36 μM
Compound: 31
Concentration required to reduce viral plaque formation by Human Cytomegalovirus (HCMV) (strain AD-169) in MRC-5 cells
Concentration required to reduce viral plaque formation by Human Cytomegalovirus (HCMV) (strain AD-169) in MRC-5 cells
[PMID: 10966740]
Molecular Weight

391.36

Formula

C14H13N7O5S
CAS No.
SMILES

O=C(C1=C(C#N)CN(C[C@@H]2NC(/C(C3=CSC(N)=N3)=N\OC)=O)N1C2=O)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LY 255262 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY 255262122620-16-0LY255262LY-255262Bacterialtaphylococcus aureusStreptococcus pneumoniaeHaemophilus influenzaEscherichia coliKlebsiellaEnterobacter aerogenesSerratiaInhibitorinhibitorinhibit

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