Lyso-monosialoganglioside GM2 ammonium
Lyso-monosialoganglioside GM2 (LysoGM2) ammonium is a lysosphingolipid and protein kinase C inhibitor (IC50: 50 μM). Lyso-monosialoganglioside GM2 ammonium can inhibit the binding of protein kinase C to Phorbol 12,13-dibutyrate (HY-18985). Lyso-monosialoganglioside GM2 ammonium is a specific biomarker for GM2 gangliosidosis. Lyso-monosialoganglioside GM2 ammonium can be used in the research of sphingolipidoses.
For research use only. We do not sell to patients.
- Formula: C49H90N4O25
- Molecular Weight:1135.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 1135.25
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Formula C49H90N4O25
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SMILES
N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@H]2[C@H](O)[C@@H](O[C@@]3(C[C@@H]([C@H]([C@@]([H])(O3)[C@H](O)[C@@H](CO)O)NC(C)=O)O)C([O-])=O)[C@@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O)[C@H]4NC(C)=O)[C@@H](CO)O2)[C@H](O)[C@H]1O)[C@@H](/C=C/CCCCCCCCCCCCC)O.[NH4+]
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Synonyms
LysoGM2 ammonium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ducatez F, et al. Lysosphingolipid Quantitation in Plasma and Dried-Blood Spots Using Targeted High-Resolution Mass Spectrometry. J Clin Lab Anal. 2025 Jan;39(1):e25131. [Content Brief]
[2]. Hannun YA, et al. Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses. Science. 1987 Feb 6;235(4789):670-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lyso-monosialoganglioside GM2 ammonium Related Classifications
HY-172546 Related Classifications
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