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  6. M2 Peptide

M2 Peptide is a peptide targeting M2-like tumor-associated macrophages (TAMs). M2 Peptide is used to carry drugs or small interfering RNA (siRNA) to promote the repolarization of M2-like macrophages to M1-like macrophages, thereby altering the immunosuppressive state in the tumor microenvironment and enhancing the anti-tumor immune response. M2 Peptide can be used to study the effect of macrophage polarization and how this polarization change affects tumor growth and metastasis.

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M2 Peptide

M2 Peptide Chemical Structure

CAS No. : 3098205-40-1

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Based on 1 publication(s) in Google Scholar

M2 Peptide Related Antibodies

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Description

M2 Peptide is a peptide targeting M2-like tumor-associated macrophages (TAMs). M2 Peptide is used to carry drugs or small interfering RNA (siRNA) to promote the repolarization of M2-like macrophages to M1-like macrophages, thereby altering the immunosuppressive state in the tumor microenvironment and enhancing the anti-tumor immune response. M2 Peptide can be used to study the effect of macrophage polarization and how this polarization change affects tumor growth and metastasis[1].

In Vitro

M2 Peptide reduces immune side effects when incorporated into a pH-sheddable micellar nanodrug by avoiding M2-targeted delivery in neutral-pH healthy organs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

M2 Peptide Related Antibodies
Molecular Weight

1759.93

Formula

C86H106N18O21S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Tyr-Trp-Trp-Lys-Val-Gly-Trp-Pro-Asp-Gln-Glu-Tyr-Cys
Sequence Shortening

YWWKVGWPDQEYC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation
References
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M2 Peptide Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

M2 Peptide3098205-40-1OthersM2-like macrophagesBALB/C micetumor-associated macrophagesIKKβGFP-4T1 cancer cells4T1 breast cancerSTAT6M1-like macrophagestumor microenvironmentsprimary murine bone marrow-derived M2-like macrophagesInhibitorinhibitorinhibit

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