Magnesium acetate tetrahydrate, for molecular biology
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Magnesium acetate tetrahydrate, for molecular biology is a carboxylic acid and short-chain fatty acid (SCFAs). Magnesium acetate tetrahydrate, for molecular biology activates AMPK, increases ROS, cleaved caspase 9, PPARα, downregulates SREBP-1c, ChREBP expression. Magnesium acetate tetrahydrate, for molecular biology exhibits antifungal activity against Saccharomyces cerevisiae W303-1A. Magnesium acetate tetrahydrate, for molecular biology regulates energy metabolism. Magnesium acetate tetrahydrate, for molecular biology has anticancer activity against gastric cancer. Magnesium acetate tetrahydrate, for molecular biology induces writhing reaction and ulcerative colitis. Magnesium acetate tetrahydrate, for molecular biology can be used in the researches for gastric cancer, ulcerative colitis, hepatic steatosis, and pain.
For research use only. We do not sell to patients.
- CAS No.: 16674-78-5
- Formula: C4H14MgO8
- Molecular Weight:214.45
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-Y0319G
Magnesium acetate tetrahydrate -
HY-W019981B
Magnesium chloride hexahydrate, for molecular biology -
HY-W019981C
Magnesium chloride hexahydrate, for cell culture -
HY-Y1110H
Magnesium chloride anhydrous, suitable for insect cell culture -
HY-Y1110I
Magnesium chloride, for insect cell culture, 97% -
HY-107754
Cesium chloride -
HY-W094475C
Magnesium sulfate heptahydrate, for cell culture -
HY-Y1267D
Magnesium sulfate, for cell culture -
HY-Y1267
Magnesium sulfate -
HY-Y0756
Sodium bicarbonate -
HY-Y0283
Potassium iodide ,meet Ch.P -
HY-W251598C
Sodium bicarbonate, for cell culture
Biological Activity
Description
In Vitro
Magnesium acetate tetrahydrate (Acetic acid; 2-5 μM; 24 h) induces cancer cell-selective death in gastric cancer cells (RGK1) via oxidative stress, while having minor effects on normal gastric mucosal cells (RGM1)[3].
Magnesium acetate tetrahydrate (Acetic acid; 20-200 mM; 200 min) induces programmed cell death in Saccharomyces cerevisiae W303-1A[4].
Magnesium acetate tetrahydrate (Acetic acid; 5 mM; 15 d) suppresses the increase in disaccharidase activity (sucrase, maltase, trehalase, lactase) in Caco-2 cells without affecting cell growth or glucose transport[5].
Magnesium acetate tetrahydrate (Acetic acid; 8-7.2 mM; 3 h) activates the AMPKα signaling pathway by consuming ATP to increase the AMP/ATP ratio in bovine hepatocytes, upregulating lipid oxidation genes, downregulating lipogenic genes, and reducing intracellular triglyceride content[6].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Magnesium acetate tetrahydrate Acetic acid (Acetic acid; 5% v/v; rectal instillation) induces ulcerative colitis in mice, causing weight loss, diarrhea, colonic inflammation, and tissue damage[8].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 16674-78-5
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Appearance Solid
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Molecular Weight 214.45
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Formula C4H14MgO8
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Color White to off-white
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SMILES
[Mg(CH3CO2)2.4H2O]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
H2O : ≥ 100 mg/mL (466.31 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[2]. Terasaki M, et al. Acetic acid is an oxidative stressor in gastric cancer cells. J Clin Biochem Nutr. 2018 Jul;63(1):36-41. [Content Brief]
[3]. Ludovico P, et al. Saccharomyces cerevisiae commits to a programmed cell death process in response to acetic acid. Microbiology (Reading). 2001 Sep;147(Pt 9):2409-2415. [Content Brief]
[4]. Ogawa N, et al. Acetic acid suppresses the increase in disaccharidase activity that occurs during culture of caco-2 cells. J Nutr. 2000 Mar;130(3):507-13. [Content Brief]
[5]. Li X, et al. Acetic acid activates the AMP-activated protein kinase signaling pathway to regulate lipid metabolism in bovine hepatocytes. PLoS One. 2013 Jul 4;8(7):e67880. [Content Brief]
[6]. Stevenson GW, et al. Targeting pain-suppressed behaviors in preclinical assays of pain and analgesia: effects of morphine on acetic acid-suppressed feeding in C57BL/6J mice. J Pain. 2006 Jun;7(6):408-16. [Content Brief]
[7]. Niu X, et al. Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice. Toxicol Appl Pharmacol. 2013 Mar 15;267(3):256-65. [Content Brief]
[8]. Granado-Serrano AB, et al. Faecal bacterial and short-chain fatty acids signature in hypercholesterolemia. Sci Rep. 2019 Feb 11;9(1):1772. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.6631 mL | 23.3155 mL | 46.6309 mL | 116.5773 mL |
| 5 mM | 0.9326 mL | 4.6631 mL | 9.3262 mL | 23.3155 mL | |
| 10 mM | 0.4663 mL | 2.3315 mL | 4.6631 mL | 11.6577 mL | |
| 15 mM | 0.3109 mL | 1.5544 mL | 3.1087 mL | 7.7718 mL | |
| 20 mM | 0.2332 mL | 1.1658 mL | 2.3315 mL | 5.8289 mL | |
| 25 mM | 0.1865 mL | 0.9326 mL | 1.8652 mL | 4.6631 mL | |
| 30 mM | 0.1554 mL | 0.7772 mL | 1.5544 mL | 3.8859 mL | |
| 40 mM | 0.1166 mL | 0.5829 mL | 1.1658 mL | 2.9144 mL | |
| 50 mM | 0.0933 mL | 0.4663 mL | 0.9326 mL | 2.3315 mL | |
| 60 mM | 0.0777 mL | 0.3886 mL | 0.7772 mL | 1.9430 mL | |
| 80 mM | 0.0583 mL | 0.2914 mL | 0.5829 mL | 1.4572 mL | |
| 100 mM | 0.0466 mL | 0.2332 mL | 0.4663 mL | 1.1658 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Magnesium acetate tetrahydrate, for molecular biology Related Classifications
HY-Y0319G1 Related Classifications
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