MAO-B-IN-59
MAO-B-IN-59 is a reversible, selective competitive inhibitor of MAO-B, with an IC50 of 0.082 μM against human MAO-B, and exhibits moderate blood-brain barrier permeability. MAO-B-IN-59 can be used in the research of Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 1163744-36-2
- Formula: C17H11ClO2
- Molecular Weight:282.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hMAO-B 82 nM (IC50) |
MAO-B-IN-59 (BF2) (0.1-0.17 μM; 0-30 min) acts as a reversible inhibitor of recombinant human MAO-B, with no time-dependent binding and activity recovery after dialysis consistent with reversible inhibition[1].
MAO-B-IN-59 (6.25-100 μg/mL) is non-cytotoxic to mouse fibroblast L929 cells at concentrations up to 25 μg/mL, with an IC50 of 55.84 μg/mL (197.51 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1163744-36-2
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Molecular Weight 282.72
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Formula C17H11ClO2
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SMILES
O=C(C1=CC2=CC=CC=C2O1)/C=C/C3=CC=CC=C3Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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