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  3. Menin-MLL inhibitor 19

Menin-MLL inhibitor 19 

Cat. No.: HY-139076
Handling Instructions

Menin-MLL inhibitor 19, a potent exo-aza spiro inhibitor of menin-mll interaction, example A17, extracted from patent WO2019120209A1. Menin-MLL inhibitor 19 can be used for the reseaech of various diseases, such as cancer, myelodysplastic syndrome (MDS) and diabetes.

For research use only. We do not sell to patients.

Menin-MLL inhibitor 19 Chemical Structure

Menin-MLL inhibitor 19 Chemical Structure

CAS No. : 2360487-93-8

Size Price Stock Quantity
5 mg USD 860 In-stock
Estimated Time of Arrival: December 31
10 mg USD 1390 In-stock
Estimated Time of Arrival: December 31
25 mg USD 2780 In-stock
Estimated Time of Arrival: December 31
50 mg USD 4450 In-stock
Estimated Time of Arrival: December 31
100 mg USD 7200 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Menin-MLL inhibitor 19, a potent exo-aza spiro inhibitor of menin-mll interaction, example A17, extracted from patent WO2019120209A1. Menin-MLL inhibitor 19 can be used for the reseaech of various diseases, such as cancer, myelodysplastic syndrome (MDS) and diabetes[1].

IC50 & Target

IC50: menin-mll interaction[1]

Molecular Weight

645.70

Formula

C₃₀H₃₄F₃N₇O₄S

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (309.74 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5487 mL 7.7435 mL 15.4871 mL
5 mM 0.3097 mL 1.5487 mL 3.0974 mL
10 mM 0.1549 mL 0.7744 mL 1.5487 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 5 mg/mL (7.74 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 5 mg/mL (7.74 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 5 mg/mL (7.74 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Menin-MLL inhibitor 19
Cat. No.:
HY-139076
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