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United States

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Cat. No.: HY-162773

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MET-IN-1

MET-IN-1 (Compound 13) is an orally active MET inhibitor. MET-IN-1 has antitumor activity.

For research use only. We do not sell to patients.

Formula: C₃₀H₂₃F₃N₁₀O₂
Molecular Weight:612.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

MET-IN-1 Chemical Structure

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Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MET-IN-1 (Compound 13) is an orally active MET inhibitor. MET-IN-1 has antitumor activity^[1].

Chemical Information

Molecular Weight 612.56
Formula C₃₀H₂₃F₃N₁₀O₂
SMILES

O=C(NC(C=C1F)=C(C=C1N(C2=NC=CN3C2=CC=N3)[C@H]4C[C@@H](C4)C5=NN(C=C5)C)F)C6=CC=NN(C6=O)C7=NC=C(C=C7)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bumpers QA, et al. Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy. J Med Chem. 2024 Aug 1. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Minimum order quantity

100 mg

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