country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187611

Copy Link Print Information

Metazide

Metazide is an antitubercular agent with non-mutagenic properties. Metazide does not induce gene mutations in Salmonella typhimurium tester strains TA 1950 and TA 1538 with in vitro metabolic activation via modified Ames plate technique. Metazide can be used for the research of tuberculosis.

For research use only. We do not sell to patients.

CAS No.: 1707-15-9
Formula: C₁₃H₁₄N₆O₂
Molecular Weight:286.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Metazide Chemical Structure

CAS No.: 1707-15-9

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Metazide does not induce gene mutations in Salmonella typhimurium strains TA 1950 and TA 1538 when tested via the semiquantitative plate Ames technique with in vitro metabolic activation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 1707-15-9
Molecular Weight 286.30
Formula C₁₃H₁₄N₆O₂
SMILES

O=C(NNCNNC(=O)C=1C=CN=CC1)C=2C=CN=CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Animals and Diseases

Genotoxicity/Mutagenicity Study
The bacterial reverse mutation assay detects point mutations that restore amino-acid prototrophy in auxotrophic Salmonella typhimurium or Escherichia coli tester strains; after exposure to a test article, mutagenic activity is read out as an increased number of revertant colonies on minimal agar compared with the vehicle control. The assay uses tester strains with different mutation targets so that base-substitution and frameshift mutagens can be detected, and testing is performed with and without exogenous mammalian metabolic activation because some chemicals require biotransformation to become mutagenic.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Shapiro A A, Meksin V A, Abilev S K, et al. Mutagenic activity of antitubercular preparations: isonicotinic acid hydrazide and its derivatives[J]. Tsitologiia i Genetika, 1978, 12(4): 343-348.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote