Mtb-IN-14
Mtb-IN-14 is a Mycobacterium tuberculosis (Mtb) malate synthase (GlcB) inhibitor with an IC50 of 0.24 μM. Mtb-IN-14 inhibits growth of Mycobacterium tuberculosis. Mtb-IN-14 can be used for the research of tuberculosis.
For research use only. We do not sell to patients.
- CAS No.: 1224740-41-3
- Formula: C10H7FO4
- Molecular Weight:210.16
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Mtb-IN-14 (Compound 2) (20 min) potently inhibits purified C619A mutant Mtb malate synthase (GlcB) with an IC50 of 0.24 μM[1].
Mtb-IN-14 has a half-life of 12 days in cell growth media or buffer solutions[1].
Mtb-IN-14 has a λmax of 333 nm, reflecting reduced structural conjugation compared to the parent PDKA compound[1].
Mtb-IN-14 inhibits growth of Mtb mc2-7000 with an MIC99 of >200 μM in acetate-supplemented media and 200 μM in dextrose-supplemented media[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1224740-41-3
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Molecular Weight 210.16
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Formula C10H7FO4
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SMILES
OC(/C(O)=C/C(C1=C(C=CC=C1)F)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mtb-IN-14 Related Classifications
HY-185453 Related Classifications
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