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  4. N-(2-Hydroxypropyl)methacrylamide

N-(2-Hydroxypropyl)methacrylamide 

Cat. No.: HY-W077028 Purity: ≥98.0%
COA Handling Instructions

N-(2-Hydroxypropyl)methacrylamide is used to synthesize copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis (VL) .

For research use only. We do not sell to patients.

N-(2-Hydroxypropyl)methacrylamide Chemical Structure

N-(2-Hydroxypropyl)methacrylamide Chemical Structure

CAS No. : 21442-01-3

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 61 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 61 In-stock
Estimated Time of Arrival: December 31
Solid
500 mg USD 55 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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  • Purity & Documentation

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Description

N-(2-Hydroxypropyl)methacrylamide is used to synthesize copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis (VL) [1][1].

In Vivo

At 5 mg/kg body weight drug equivalent dose, all N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates which contained lysosomally degradable side chains shows significant in vivo antileishmanial activity (>99% inhibition)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

143.18

Appearance

Solid

Formula

C7H13NO2
CAS No.
SMILES

C=C(C)C(NCC(O)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (698.42 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9842 mL 34.9211 mL 69.8422 mL
5 mM 1.3968 mL 6.9842 mL 13.9684 mL
10 mM 0.6984 mL 3.4921 mL 6.9842 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (17.46 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (17.46 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (17.46 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 98.87%

COA (244 KB) HNMR (125 KB) GC (125 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

N-(2-Hydroxypropyl)methacrylamide21442-01-3OtherssynthesizecopolymersdeliveryantileishmanialagentsVisceralleishmaniasisVLInhibitorinhibitorinhibit

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N-(2-Hydroxypropyl)methacrylamide
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