N-myristoyl-RKRTLRRL
Based on 1 Customer Validation
N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM. histone phosphorylation with IC50 of 80 μM.
For research use only. We do not sell to patients.
- Purity: 99.37%
- CAS No.: 152246-40-7
- Formula: C60H117N21O11
- Molecular Weight:1308.71
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 152246-40-7
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Appearance Solid
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Molecular Weight 1308.71
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Formula C60H117N21O11
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Color White to off-white
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Sequence
{Myr}-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu
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Sequence Shortening
{Myr}-RKRTLRRL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (38.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. David K Crockett, et al. Identification of proteins from formalin-fixed paraffin-embedded cells by LC-MS/MS. Lab Invest. 2005 Nov;85(11):1405-15. [Content Brief]
[2]. C A O'Brian, et al. A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to Adriamycin. Invest New Drugs. 1991 May;9(2):169-79. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7641 mL | 3.8206 mL | 7.6411 mL | 19.1028 mL |
| 5 mM | 0.1528 mL | 0.7641 mL | 1.5282 mL | 3.8206 mL | |
| 10 mM | 0.0764 mL | 0.3821 mL | 0.7641 mL | 1.9103 mL | |
| 15 mM | 0.0509 mL | 0.2547 mL | 0.5094 mL | 1.2735 mL | |
| 20 mM | 0.0382 mL | 0.1910 mL | 0.3821 mL | 0.9551 mL | |
| 25 mM | 0.0306 mL | 0.1528 mL | 0.3056 mL | 0.7641 mL | |
| 30 mM | 0.0255 mL | 0.1274 mL | 0.2547 mL | 0.6368 mL |
N-myristoyl-RKRTLRRL Related Classifications
HY-P5988 Related Classifications
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