2. Apoptosis
  3. Necroptosis RIP kinase
  4. Necroptosis-IN-5

Necroptosis-IN-5 (Compound 26) is an orally active necroptosis inhibitor. Necroptosis-IN-5 also exhibits potent inhibitory activity against receptor-interacting protein kinase 1 (RIPK1). Necroptosis-IN-5 can be used to study necroptosis-related inflammatory diseases, neurodegenerative diseases, and cancers.

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Necroptosis-IN-5

Necroptosis-IN-5 Estructura química

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Necroptosis-IN-5 Related Antibodies

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RIPK1 RIPK2 RIPK3

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Descripciòn

Necroptosis-IN-5 (Compound 26) is an orally active necroptosis inhibitor. Necroptosis-IN-5 also exhibits potent inhibitory activity against receptor-interacting protein kinase 1 (RIPK1). Necroptosis-IN-5 can be used to study necroptosis-related inflammatory diseases, neurodegenerative diseases, and cancers[1].

IC50 & Target

RIPK1

 

Peso molecular

542.60

Fòrmula

C30H31FN6O3
SMILES

CC1=CC=C(OCCN2CCOCC2)C=C1C3=CC=NC(NC(C4=NN5C([C@@H](F)C[C@H]5C6=CC=CC=C6)=N4)=O)=C3
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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Necroptosis-IN-5 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Necroptosis-IN-5NecroptosisRIP kinaseReceptor-interacting protein kinasesRIPKanti-necroptoticRIPK1inflammatoryneurodegenerativecancerInhibitorinhibitorinhibit

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Nombre del producto:
Necroptosis-IN-5
Cat. No.:
HY-161911
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