NOTA-SP2A-FAPT
NOTA-SP2A-FAPT is a fibroblast activation protein (FAP) ligand. NOTA-SP2A-FAPT can be adiolabeled and exhibits rapid renal excretion with fast kidney tissue clearance, accumulates rapidly in and retains high levels in FAP-positive tumor xenografts to enable clear tumor visualization. NOTA-SP2A-FAPT can be used as a tracer of cancer.
For research use only. We do not sell to patients.
- Formula: C52H73F2N13O20S2
- Molecular Weight:1302.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
NOTA-SP2A-FAPT exhibits high binding affinity to human FAP (binding energy: -9.0 kcal/mol) and moderate binding to human serum albumin (binding energy: -7.7 kcal/mol)[1].
NOTA-SP2A-FAPT competitively binds [18F]AlF-NOTA-FAPI-42 in A549-FAP cells with IC50 of 8.58 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1302.34
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Formula C52H73F2N13O20S2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NOTA-SP2A-FAPT Related Classifications
HY-P11599 Related Classifications
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