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Cat. No.: HY-P1721

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NPC 17731

NPC 17731 is a new bradykinin (BK) receptor antagonist. NPC 17731 antagonized both the contractile and relaxant responses caused by BK in longitudinal smooth muscle with IC₅₀ of 23 and 29 nM, respectively.

For research use only. We do not sell to patients.

CAS No.: 147267-10-5
Formula: C₅₉H₉₅N₁₉O₁₄
Molecular Weight:1294.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NPC 17731 Chemical Structure

CAS No.: 147267-10-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Bradykinin Receptor Isoforms :

Chemical Information

CAS No. 147267-10-5
Molecular Weight 1294.50
Formula C₅₉H₉₅N₁₉O₁₄
Sequence

Arg-Arg-Pro-{Hyp}-Gly-Phe-Ser-{Hyp}-{Oic}-Arg
Sequence Shortening

RRP-{Hyp}-GFS-{Hyp}-{Oic}-R
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Y S Medeiros, et al. Competitive and selective antagonistic action of NPC 17731 on bradykinin-induced relaxant and contractile responses of the guinea pig isolated ileum. Gen Pharmacol. 1995 Nov;26(7):1507-11. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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NPC 17731

All Bradykinin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

NPC 17731 Related Classifications

HY-P1721 Related Classifications