823 Results for "

B3

" in MedChemExpress (MCE) Product Catalog:
Products (823)

823 Results for "B3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-B0143S2
CAS No.: 66148-15-0
Synonyms: Nicotinic acid-d4; Vitamin B3-d4
Research Areas:  

Metabolic Disease

Niacin-d4 (Nicotinic acid-d4) is the deuterium labeled Niacin (HY-B0143). Niacin (Nicotinic acid) is a vitamin and is part of the vitamin B group.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P99905
CAS No.: 2375661-82-6
Synonyms: IBI302

Target:  

VEGFR

Efdamrofusp alfa is a bispecific fusion protein. Efdamrofusp alfa is capable of neutralizing both VEGF isoforms and C3b/C4b. Efdamrofusp alfa can be used for the research of neovascular age-related macular degeneration (nAMD) and other complement-related ocular conditions .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-147918
CAS No.: 124811-87-6
Purity:  99.92%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Anticancer agent 73 (compound CIB-3b) is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-112776A
CAS No.: 1049740-43-3
Purity:  99.36%
Target:  

Phosphatase

Research Areas:  

Cancer

BN82002 hydrochloride is a potent, selective and irreversible inhibitor of CDC25 phosphatase family. BN82002 hydrochloride inhibits CDC25A, CDC25B2, CDC25B3, CDC25C CDC25A, and 25C-cat with IC50 values of 2.4, 3.9, 6.3, 5.4, and 4.6 µM, respectively. BN82002 hydrochloride displays ~20-fold greater selectivity over CD45 tyrosine phosphatase .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-N7755
CAS No.: 14982-12-8
Estradiol 3-glucuronide sodium is an estrogen metabolite, which is a glucuronide conjugate formed by the catalysis of uridine diphosphate glucuronosyltransferase in tissues such as the liver from Estradiol (HY-B0141). Estradiol 3-glucuronide sodium is a potent substrate of Mrp2, with an S50 of 55.7 μM. Estradiol 3-glucuronide sodium achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP [3].
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W585842
CAS No.: 15270-30-1
Estradiol 3-glucuronide is an estrogen metabolite, which is a glucuronide conjugate formed from Estradiol (HY-B0141) via catalysis by uridine diphosphate glucuronosyltransferases in tissues such as the liver. Estradiol 3-glucuronide is a potent substrate of Mrp2, with an S50 value of 55.7 μM. Estradiol 3-glucuronide achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP [3].
loading...
    loading...
Cat. No.: HY-N6726
CAS No.: 1422359-85-0
Fumonisin B3 is an orally active fumonisin Mycotoxin. Fumonisin B3 can be isolated from Fusarium moniliforme, Fusarium proliferatum and Fusarium nygamai. Fumonisin B3 induces precancerous lesions, triggers embryonic death of chicken embryos, causes severe hemorrhage in dead chicken embryos. Fumonisin B3 can be used in studies related to hepatocellular carcinoma .
loading...
    loading...
Cat. No.: HY-P991200

Target:  

HCV Claudin

Research Areas:  

Infection

OM-7D3-B3 is an antibody-based antiviral agent targeting the tight junction protein CLDN1 (Kd=4 nM). By binding to the first extracellular domain of CLDN1, OM-7D3-B3 disrupts the formation of the CLDN1-CD81 co-receptor complex, thereby effectively inhibiting the entry of hepatitis C virus (HCV). OM-7D3-B3 not only prevents de novo and chronic HCV infections in humanized liver chimeric mice and uPA-SCID mice transplanted with human livers, but also exhibits favorable safety with no toxic effects observed. OM-7D3-B3 serves as a critical tool for research on HCV infection mechanisms and antiviral drug development .
loading...
    loading...
Cat. No.: HY-N0623S5
CAS No.: 1233395-93-1
Synonyms: Tryptophan-d8; Tryptophane-d8
L-Tryptophan-d8 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
loading...
    loading...
Cat. No.: HY-N0623S9
CAS No.: 133519-78-5
Synonyms: Tryptophan-d3; Tryptophane-d3
L-Tryptophan-d3 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
loading...
    loading...
Cat. No.: HY-N0623S3
CAS No.: 81201-92-5
Synonyms: Tryptophan-1-13C; Tryptophane-1-13C
L-Tryptophan-1- 13C is the 13C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
loading...
    loading...
Cat. No.: HY-N0623S8
CAS No.: 204634-20-8
Synonyms: Tryptophan-15N2; Tryptophane-15N2
L-Tryptophan- 15N2 is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3 .
loading...
    loading...
Cat. No.: HY-113445
CAS No.: 71953-80-5
Purity:  ≥95.0%
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease Cancer

Thromboxane B3 is an eicosanoid and the stable hydrolysis product of thromboxane A3, which is synthesized from eicosapentaenoic acid by cyclooxygenase (COX) and thromboxane synthase. Thromboxane B3 participates in inflammatory cell regulation, tumorigenesis and cell proliferation processes. Elevated levels of Thromboxane B3 correlate with high-risk regions of esophageal cancer. Thromboxane B3 can be used in studies related to bladder cancer, renal cell carcinoma and esophageal squamous cell carcinoma [3].
loading...
    loading...
Cat. No.: HY-N0623S7
CAS No.: 99404-62-3
Synonyms: Tryptophan-15N; Tryptophane-15N
L-Tryptophan- 15N is the 15N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
loading...
    loading...
Cat. No.: HY-149777
CAS No.: 3033557-95-5
Purity:  99.56%
Research Areas:  

Inflammation/Immunology

B3GNT2-IN-1 is a β-1,3-N-acetylglucosaminyltransferase 2 (B3GNT2) inhibitor with an IC50 of 0.009 μM. B3GNT2-IN-1 is applicable to research related to rheumatoid arthritis, ankylosing spondylitis and psoriasis .
loading...
    loading...
Cat. No.: HY-12240
CAS No.: 294193-86-5
Target:  

Ser/Thr Kinase

Research Areas:  

Cancer

B32B3 is an inhibitor of VprBP with an IC50 value of 0.5 μM at the H2AT120p cell. B32B3 can suppress tumor growth .
loading...
    loading...
Cat. No.: HY-N0623S10
CAS No.: 84344-22-9
L-Phenylalanine,Indole- 15N is the 15N labeled L-Tryptophan[1]. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[2].
loading...
    loading...
Cat. No.: HY-177827
Target:  

Liposome

Research Areas:  

Metabolic Disease

Liposomal Vitamin B3 is a specialized delivery system that encapsulates vitamin B3 within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of vitamin B3. Vitamin B3 (Nicotinamide) is one of the water-s
loading...
    loading...
Cat. No.: HY-N4219
CAS No.: 58316-42-0
Saikosaponin B3 is a saikosaponin isolated from the roots of Bupleurum falcatum L., with analgesic effect. Saikosaponin B3 inhibits ACTH-induced lipolysis in the fat cells [3].
loading...
    loading...
Cat. No.: HY-N16549
CAS No.: 86631-41-6
Synonyms: 3-O-Galloylprocyanidin B3
Procyanidin B3-3-O-gallate (3-O-Galloylprocyanidin B3) is a selective mammalian DNA polymerase α inhibitor, with a calf DNA polymerase α IC50 of 0.26 μM. Procyanidin B3-3-O-gallate scavenges DPPH radicals. Procyanidin B3-3-O-gallate can be used for research on oxidative stress and inflammatory diseases[1].
loading...
    loading...