PAANIB-1
PAANIB-1 is a parthanatos associated apoptosis-inducing factor nuclease (PAAN)/macrophage migration inhibitor factor (MIF) inhibitor. PAANIB-1 exhibits neuroprotective activity. PAANIB-1 can be used for the research of Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 2634726-71-7
- Formula: C62H81FN6O15
- Molecular Weight:1169.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
PAANIB-1 (Compound 154) (10 μM; 1 h preincubation) inhibits 38.2% MIF activity and protects SH-SY5Y cells against MNNG (HY-128612)-induced cell death[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SH-SY5Y human neuroblastoma cells
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Concentration:10 μM
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Incubation Time:1 h (pre-incubation); 15 min (MNNG)
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Result:Reduced 46.2% MNNG-induced cell death in SH-SY5Y cells.
Chemical Information
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CAS No. 2634726-71-7
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Molecular Weight 1169.34
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Formula C62H81FN6O15
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SMILES
O=C1N2[C@@](C(N(CC/C=C/C(OCC(C)(C(C(N3[C@](CCCC3)([H])C(O[C@@H](C4=CC(F)=CC(OCC(N([C@H](C(N[C@@H](C5=CC=CC=C5)C(N([C@H]1COC(C)(C)C)C)=O)=O)C)C)=O)=C4)CCC6=CC(OC)=C(C=C6)OC)=O)=O)=O)C)=O)C)=O)([H])CCC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PAANIB-1 Related Classifications
HY-182935 Related Classifications
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