2. Neuronal Signaling Protein Tyrosine Kinase/RTK
  3. Trk Receptor
  4. Pan-Trk-IN-2

Compound cpd-1 is a small molecule Trks inhibitor with good antitumor activity.

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Pan-Trk-IN-2

Pan-Trk-IN-2 Estructura química

No. CAS : 2583778-77-0

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Pan-Trk-IN-2 Related Antibodies

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TrkA TrkB TrkC Trk

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Descripciòn

Compound cpd-1 is a small molecule Trks inhibitor with good antitumor activity[1].

Cellular Effect
Cell Line Type Value Description References
BaF3 IC50
1.352 μM
Compound: Cpd 1
Cytotoxicity against mouse BaF3 cells harboring TEL fused TrkC G613R mutant assessed as inhibition of cell growth by MTT assay
Cytotoxicity against mouse BaF3 cells harboring TEL fused TrkC G613R mutant assessed as inhibition of cell growth by MTT assay
[PMID: 35080890]
Peso molecular

506.86

Fòrmula

C22H18ClF3N6O3
No. CAS
SMILES

O=C(NC1=CC=C(C(C(F)(F)F)=C1)Cl)NC2=CC=C(NC(N=CN=C3N4)=C3OC(C)(C)C4=O)C=C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

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Pureza y Documentación
Referencias
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Pan-Trk-IN-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pan-Trk-IN-22583778-77-0Trk ReceptorTropomyosin related kinase receptorInhibitorinhibitorinhibit

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Nombre del producto:
Pan-Trk-IN-2
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HY-144028
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