PD-1/PD-L1-IN-42
Based on 1 Customer Validation
PD-1/PD-L1-IN-42 (Compound B8.4) is an inhibitor of the interaction between PD-1 and PD-L1, with an EC50 of 0.1 μM. PD-1/PD-L1-IN-42 can be used for the research of cancer immunotherapy.
For research use only. We do not sell to patients.
- Purity: 99.82%
- Formula: C85H129N21O24S
- Molecular Weight:1861.13
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
EC50: 0.1 μM (PD-1/PD-L1)[1].
Chemical Information
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Appearance Solid
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Molecular Weight 1861.13
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Formula C85H129N21O24S
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Color White to off-white
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Sequence
Thr-Arg-Ser-Pro-Ile-Cys-Tyr-Gln-Ile-Ile-Asp-Tyr-Lys-Phe-Asn
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Sequence Shortening
TRSPICYQIIDYKFN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (53.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.5373 mL | 2.6865 mL | 5.3731 mL | 13.4327 mL |
| 5 mM | 0.1075 mL | 0.5373 mL | 1.0746 mL | 2.6865 mL | |
| 10 mM | 0.0537 mL | 0.2687 mL | 0.5373 mL | 1.3433 mL | |
| 15 mM | 0.0358 mL | 0.1791 mL | 0.3582 mL | 0.8955 mL | |
| 20 mM | 0.0269 mL | 0.1343 mL | 0.2687 mL | 0.6716 mL | |
| 25 mM | 0.0215 mL | 0.1075 mL | 0.2149 mL | 0.5373 mL | |
| 30 mM | 0.0179 mL | 0.0896 mL | 0.1791 mL | 0.4478 mL | |
| 40 mM | 0.0134 mL | 0.0672 mL | 0.1343 mL | 0.3358 mL | |
| 50 mM | 0.0107 mL | 0.0537 mL | 0.1075 mL | 0.2687 mL |
PD-1/PD-L1-IN-42 Related Classifications
HY-P10217 Related Classifications
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